Anatomic Morphologic Analysis of MR Brain Images

R01 NS34189

Principal Investigator: David Kennedy


Publications resulting from this research:

Manuscripts:

Submitted:

Shah, J. "H0 type Riemannian metrics on the space of planar curves", Submitted to the Journal of Differential Geometry.

Shi, Y. and W. C. Karl, A Real-Time Algorithm For The Approximation Of Level-Set-Based Curve Evolution,, Submitted to IEEE Trans. on Image Processing.

2006

Caplan, D., G. Waters, G. DeDe, J. Michaud, A. Reddy, N. Alpert, DN. Kennedy, N. Makris. A Study of Syntactic Processing in Aphasia I: Behavioral (Psycholinguistic) Aspects. Brain and Language, In Press.

Caplan, D., G. Waters, G. DeDe, J. Michaud, A. Reddy, N. Alpert, DN. Kennedy, N. Makris. A Study of Syntactic Processing in Aphasia II: Neurological Aspects. Brain and Language, In Press.

Desai, M., R Mangoubi “Robust Subspace Learning and Detection in Laplacian Noise and Interference”, accepted IEEE Trans. on Signal Processing, 2006.

Desai, M., D. Kennedy, et al “Model-Based Variational Smoothing and Segmentation for Diffusion Tensor Imaging in the Brain”, Neuroinformatics, 4(3):217-34, 2006. PubMed

Jovicich, J., Czanner, S., Greve, D., Haley, E., van der Kouwe, A., Gollub, R., Kennedy, D., et al. Reliability in multi-site structural MRI studies: effects of gradient non-linearity correction on phantom and human data. Neuroimage, 2006. 30(2): p. 436-43. PubMed

Kennedy, D.N. and C. Haselgrove, The Internet Analysis Tools Registry: A Public Resource for Image Analysis. Neuroinformatics, 2006. PubMed

Litvin, W. C. Karl, J. Shah, Shape and appearance modeling with feature distributions for image segmentation, Proceedings of the 2006 IEEE International Symposium on Biomedical Imaging, Arlington, VA, April 6-9, 2006.

Makris, N., Goldstein, JM., Kennedy, DN. et al., Decreased volume of left and total anterior insular lobule in schizophrenia. Schizophr Res, 2006. 83(2-3): p. 155-71.

Shah, J. “Skeletons and segmentation of shapes”, in Medial Representations: Mathematics, Algorithms and Applications, Ed: S. Pizer, P. Yushkevich and K. Siddiqi, In Press.

Shah, J. “An H2-type Riemannian metric on the space of planar curves”, acepted to the MICCAI workshop on Mathematical Foundations of Computational Anatomy.

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2005

Desai, M, Mangoubi, R. and Pien, H. Functional MRI Activity Characterization: An Estimation and Decision Theoretic Approach, to appear in Medical Imaging Systems: Methods in Diagnosis Optimization (Vol. 4) edited by Dr. Corenelius T. Leondes, World Scientific Publishing Co

Kennedy DN. Barriers to the Socialization of Information, Editorial. Neuroinformatics. 2004;2(4):367-8. PubMed

Litvin, A. and Karl, WC. Coupled shape distribution-based segmentation of multiple objects, Technical Report ECE-2005-01, ECE department, Boston University, 2005

Litvin, A. and Karl, WC. Coupled shape distribution-based segmentation of multiple objects, Proceeding of Information Processing in Medical Imaging (IPMI 2005), Glenwood Springs, Colorado, 2005.

Herbert MR, Ziegler DA, Deutsch CK, O'Brien LM, Kennedy DN, Filipek PA, Bakardjiev AI, Hodgson J, Takeoka M, Makris N, Caviness VS Jr. Brain asymmetries in autism and developmental language disorder: a nested whole-brain analysis. Brain. 2005 Jan;128(Pt 1):213-26. PubMed

Makris N, Schlerf JE, Hodge SM, Haselgrove C, Albaugh MD, Seidman LJ, Rauch SL, Harris G, Biederman J, Caviness VS Jr, Kennedy DN, Schmahmann JD. MRI-based surface-assisted parcellation of human cerebellar cortex: ananatomically specified method with estimate of reliability. Neuroimage. 2005 May 1;25(4):1146-1160. PubMed

Makris N, Kennedy DN, McInerney S, Sorensen AG, Wang R, Caviness VS Jr, Pandya DN. Segmentation of Subcomponents within the Superior Longitudinal Fascicle in Humans: A Quantitative, In Vivo, DT-MRI Study. Cereb Cortex. 2005; 15:854-869. PubMed

Shah, J. Skeletons of 3D shapes, Proceedings of the Fifth International Conference on Scale-Space and PDE Methods in Computer Vision, LNCS 3459, Springer, 2005

Shah, J. Grayscale Skeletons and Segmentation of Shape, Journal of Computer Vision and Image Understanding, 99(1):96-109, July, 2005.

Shi, Y. and Karl, W. C. “A fast level set method without solving PDEs”, Proc. 2005 IEEE Int'l Conf. on Acoustics, Speech, and Signal Processing, pg. II-97-II-100, Philadelphia, March 20-23, 2005. Student Paper Award Winner.

Shi, Y. and Karl, W. C. “Real-time tracking using level sets”, Proc. CVPR'05, Jun, 2005.

Shi, Y. and W. C. Karl, "A fast implementation of the level set method without solving partial differential equations", Technical Report ECE-2005-02, ECE Department, Boston University, Jan, 2005.

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2004

Fischl, B., van der Kouwe, A., Destrieux, C., Halgren, E., Segonne, F., Salat, D. H., Busa, E., Seidman, L. J., Goldstein, J., Kennedy, D., Caviness, V., Makris, N., Rosen, B., Dale, A. M. Automatically parcellating the human cerebral cortex. Cereb Cortex 2004; 14(1):11-22. PubMed

Desai, M. and Mangoubi, R. Non gaussian subspace learning in the presence of interfernce, 3rd IEEE Sensor Array & Multichannel Signal Proc. Workshop, Barcelona, July 2004

Desai, M, and Mangoubi, R. Non-gaussian robust matched subspace detectors and signal design analysis for a separable class of subspace filter detectors, 3rd IEEE Sensor Array & Multichannel Signal Proc. Workshop, Barcelona, July 2004

Litvin, A. and Karl, WC. Shape distributions as priors for image segmentation, in Computational Imaging, C. A. Bouman and R. L. Stevenson, editors, Proc. SPIE, Vol. 5016, SPIE, Santa Clara, CA, January 20-24, 2004.

Litvin, A. and Karl, WC. Using Shape Distributions as Priors in a Curve Evolution Framework, Proc. 2004 IEEE Int'l Conf. on Acoustics, Speech, and Signal Processing, Montreal, pg. III-25-III-28, May 17-21, 2004.

Shi, Y. and W. C. Karl, “Differentiable minimin shape distance for incorporating topological priors in biomedical imaging,” Proc. 2004 IEEE Intl. Symposium on Biomedical Imaging, pg. 1247-1250, Arlington, VA, 15-18 April, 2004.

Shi, Y. and W. C. Karl, “Differentiable Minimin Shape Distance for Maintaining Topology in Curve Evolution”, Proc. 2004 SIAM Conference on Imaging Science, Salt Lake City, Utah, May 3-5, 2004.

Shi, Y. and W. C. Karl, “Shape reconstruction for unorganized points with a data-driven level set methods”, Proc. 2004 IEEE Int'l Conf. on Acoustics, Speech, and Signal Processing, pg. III-13-III-16, Montreal, May 17-21, 2004.

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2003:

Ascoli, G. A., E. De Shutter, Kennedy, DN (2003). "An information science infrastructure for neuroscience." Neuroinformatics 1(1): 1-2. PubMed

Desai, M. and R. Mangoubi, Robust Gaussian and non-Gaussian Matched Subspace Detection. IEEE Trans. On Signal Processing, Dec 2003, pp. 3115-3127.

Desai, M, and Magngoubi R. Non Gaussian subspace learning and innovations. IEEE 37th Asilomar conference on Signals, Systems and Computers, Monterey, Calif. , November 2003

Faraone SV, Seidman LJ, Kremen WS, Kennedy D, Makris N, Caviness VS, Goldstein J, Tsuang MT. Structural brain abnormalities among relatives of patients with schizophrenia: implications for linkage studies. Schizophr Res, Apr 1;60(2-3):125-40, 2003. PubMed

Haselgrove C., and Kennedy, DN. Internet Brain Volume Database. In Proceedings of 9th International Conference on Functional Mapping of the Human Brain. New York. 2003.

Herbert MR, Ziegler DA, Deutsch CK, O'Brien LM, Lange N, Bakardjiev A, Hodgson J, Adrien KT, Steele S, Makris N, Kennedy D, Harris GJ, Caviness VS Jr. Dissociations of cerebral cortex, subcortical and cerebral white matter volumes in autistic boys. Brain. 126(Pt 5):1182-92, 2003. PubMed

Kennedy DN, Haselgrove C, McInerney S. MRI-based morphometric analysis of typical and atypical brain development Ment Retard Dev Disabil Res Rev. 9(3):155-60, 2003. PubMed

Litvin, A, Karl, WC. Level set-based segmentation using feature histogram shape priors, Proc. 2003 IEEE Workshop on Statistical Signal Processing, pg. 153-156, St. Louis, Sept. 28-Oct. 1, 2003

Makris N, Hodge SM, Haselgrove C, Kennedy DN, Dale A, Fischl B, Rosen BR, Harris G, Caviness VS Jr, Schmahmann JD. Human cerebellum: surface-assisted cortical parcellation and volumetry with magnetic resonance imaging. J Cogn Neurosci. 15(4):584-99, 2003. PubMed

Rauch SL, Phillips KA, Segal E, Makris N, Shin LM, Whalen PJ, Jenike MA, Caviness VS, Jr, Kennedy DN. A preliminary morphometric magnetic resonance imaging study of regional brain volumes in body dysmorphic disorder. Psychiatry Res, Jan 20;122(1):13-9, 2003. PubMed

Takahashi, T., Kinsman, S., Makris, N., Grant, E., Haselgrove, C., McInerney, S., Kennedy, D. N., Fredrickson, K., Mori, S., Caviness, V. S. Semilobar holoprosencephaly with midline 'seam': a topologic and morphogenetic model based upon MRI analysis. Cereb Cortex 2003; 13(12):1299-1312. PubMed

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2002:

Caviness VS, Makris N, Montinaro E, Sahin NT, Bates JF, Schwamm L, Caplan D, Kennedy DN. Anatomy of stroke, Part I: an MRI-based topographic and volumetric System of analysis. Stroke, Nov;33(11):2549-56, 2002. PubMed

Caviness, V.S., Jr. , N. Makris, E. Montinaro, N.T. Sahin, J.F. Bates, D. Caplan, and D.N. Kennedy, Anatomy Of Stroke II: Volumetric Characteristics With Implications For The Local Architecture Of The Cerebral Perfusion System: An MRI Based Analysis of MCA Embolic Infarction. Stroke, Nov;33(11):2557-64, 2002. PubMed

Desai M, Mangoubi R, Shah J, Karl W, Pien H, Worth A, Kennedy D. Functional MRI activity characterization using response time shift estimates from curve evolution. IEEE Trans Med Imaging, Nov;21(11):1402-12, 2002. PubMed

Desai, M., R. Mangoubi, Robust Matched Filter Detectors in the Presence of Signal and Interference Magnitude Constraints, IEEE 36th Asilomar conference on Signals, Systems, and Computers, Nov 2002

Fischl B, Salat DH, Busa E, Albert M, Dieterich M, Haselgrove C, van der Kouwe A, Killiany R, Kennedy D, Klaveness S, Montillo A, Makris N, Rosen B, Dale AM. Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain. Neuron, Jan 31;33(3):341-55, 2002. PubMed

Goldstein JM, Seidman LJ, O'Brien LM, Horton NJ, Kennedy DN, Makris N, Caviness VS Jr, Faraone SV, Tsuang MT. Impact of normal sexual dimorphisms on sex differences in structural brain abnormalities in schizophrenia assessed by magnetic resonance imaging. Arch Gen Psychiatry, Feb;59(2):154-64, 2002. PubMed

Herbert MR, Harris GJ, Adrien KT, Ziegler DA, Makris N, Kennedy DN, Lange NT, Chabris CF, Bakardjiev A, Hodgson J, Takeoka M, Tager-Flusberg H, Caviness VS Jr. Abnormal asymmetry in language association cortex in autism. Ann Neurol, Nov;52(5):588-96, 2002. PubMed

Kennedy, DN., Makris, N., Herbert, M. R., Takahashi, T., Caviness, V. S. Basic principles of MRI and morphometry studies of human brain development. Developmental Science, 5(3), 268-278, 2002.

Litvin, A. and W.C. Karl. Image segmentation based on prior probabilistic shape models. in IEEE Int'l Conf. on Acoustics, Speech, and Signal Processing. 2002.

Makris, N., D.N. Pandya, J.J. Normandin, G.M. Papadimitriou, S.L. Rauch, V.S. Caviness, Jr., and D.N. Kennedy, Diffusion Tensor-MRI (DT-MRI) Investigations of the Human Cingulum Bundle. CNS Spectrums, 2002; 7(7): 522-528.

Shah, J. Reaction-diffusion equations and Learning, Journal of Visual Communication and Image Representation, v.13, no.1, March, 2002.

Shah, J. Reaction-diffusion equations and learning, Proceedings of the Workshop on Variational Methods for Discontinuous Structures, Como, Italy, Progress in Nonlinear Differential Equations and Their Applications, V. 51, 2002, pp. 171-182.

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Special Conference Sessions:

2006 IEEE International Symposium on Biomedical Imaging: From Nano to Macro. Special Session, Shape in Biomedical Imaging. Co-chaired by W. Clem Karl, Boston University and Eric Miller, Northeastern University. April 6-9, 2006, at the Crystal Gateway Marriott, Arlington, Virginia, USA.

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Theses:

Y. Shi, “Object-Based Dynamic Imaging with Level-Set Methods”, Doctoral thesis, BU ECE Dept., May, 2005.

A. Litvin, “Statistical shape and appearance models for segmentation and classification”, Doctoral thesis, BU ECE Dept., May, 2006.

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